Abstract
The frequency of acute HIV infection (AHI) among HIV-1 enzyme-linked immunosorbent assay (ELISA)-negative samples received from general hospital patient admissions was assessed. Of 3,005 samples pooled for nucleic acid testing, a prevalence of 0.13% was found. Pooled nucleic acid testing may be feasible for low-cost identification of AHI in high-prevalence settings.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Enzyme-Linked Immunosorbent Assay
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HIV Antibodies / blood*
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HIV Infections / diagnosis*
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HIV Infections / epidemiology*
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HIV Infections / virology
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HIV-1 / genetics*
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HIV-1 / immunology
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HIV-1 / isolation & purification*
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Humans
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RNA, Viral / blood*
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Reverse Transcriptase Polymerase Chain Reaction
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South Africa / epidemiology
Substances
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HIV Antibodies
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RNA, Viral