Abstract
In this study, we identified critically ill patients with Acinetobacter baumannii bacteremia and examined perirectal surveillance cultures for the presence of genetically related A baumannii strains using pulsed-field gel electrophoresis to determine whether gut colonization preceded clinical infection. Seven patients with imipenem-resistant A baumannii bacteremia were identified from January to June of 2008. Six of 7 (86%) patients were colonized in the gastrointestinal tract with genetically similar strains preceding their bacteremia.
Copyright © 2010 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter Infections / microbiology*
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Acinetobacter baumannii / classification*
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Acinetobacter baumannii / drug effects
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Acinetobacter baumannii / isolation & purification
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Adult
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Aged
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Anti-Bacterial Agents / pharmacology
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Bacteremia / microbiology*
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Bacterial Typing Techniques*
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Blood / microbiology*
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Critical Illness
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Cross Infection / microbiology
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DNA Fingerprinting
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Electrophoresis, Gel, Pulsed-Field
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Female
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Gastrointestinal Tract / microbiology*
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Humans
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Imipenem / pharmacology
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Male
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Middle Aged
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Molecular Epidemiology
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beta-Lactam Resistance
Substances
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Anti-Bacterial Agents
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Imipenem