Ecthyma gangrenosum mimicking acute invasive fungal sinusitis in an immunocompromised patient

Ear Nose Throat J. 2010 Jun;89(6):262-7.

Abstract

Ecthyma gangrenosum is a rare necrotizing cutaneous infection usually caused by Pseudomonas aeruginosa. We report a case of ecthyma gangrenosum presenting as a sinonasal eschar and mimicking acute invasive fungal sinusitis in an immunocompromised 39-year-old man with a hematologic malignancy. To the best of our knowledge, this represents the first case of ecthyma gangrenosum affecting the sinonasal mucosa to be reported in the literature.

Publication types

  • Case Reports

MeSH terms

  • Acetamides / therapeutic use
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Diagnosis, Differential
  • Ecthyma / complications*
  • Ecthyma / diagnosis
  • Ecthyma / drug therapy
  • Humans
  • Immunocompromised Host*
  • Linezolid
  • Male
  • Mycoses / diagnosis
  • Mycoses / microbiology
  • Nasal Mucosa / microbiology*
  • Nasal Mucosa / pathology
  • Nasal Mucosa / surgery
  • Ofloxacin / therapeutic use
  • Oxazolidinones / therapeutic use
  • Protein Synthesis Inhibitors / therapeutic use
  • Pseudomonas Infections / diagnosis*
  • Pseudomonas Infections / drug therapy
  • Pseudomonas Infections / microbiology
  • Pseudomonas aeruginosa*
  • Pyoderma Gangrenosum
  • Risk Factors
  • Sinusitis / diagnosis*
  • Sinusitis / microbiology
  • Vancomycin / therapeutic use

Substances

  • Acetamides
  • Anti-Bacterial Agents
  • Oxazolidinones
  • Protein Synthesis Inhibitors
  • Vancomycin
  • Ofloxacin
  • Linezolid