Abstract
The in vivo activity of truncated forms of methylorcinaldehyde synthase shows that the synthase retains a hydrolytic release activity in the absence of reductive chain release and that chain-length is not controlled by the reductive release domain; experiments using a methyltransferase inhibitor suggest that methylation occurs prior to aromatisation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biocatalysis*
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Cloning, Molecular
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Fungal Proteins / chemistry*
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Fungal Proteins / metabolism
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Methylation
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Molecular Structure
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Oxidation-Reduction
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Polyketide Synthases / chemistry*
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Polyketide Synthases / genetics
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Polyketide Synthases / metabolism
Substances
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Fungal Proteins
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Polyketide Synthases