Synthesis of azaspirocycles and their evaluation in drug discovery

Angew Chem Int Ed Engl. 2010 May 3;49(20):3524-7. doi: 10.1002/anie.200907108.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemical synthesis
  • Anti-Infective Agents / pharmacology
  • Aza Compounds / chemical synthesis*
  • Aza Compounds / metabolism
  • Aza Compounds / pharmacology
  • Drug Discovery
  • Hepatocytes / metabolism
  • Humans
  • Molecular Structure
  • Spiro Compounds / chemical synthesis*
  • Spiro Compounds / metabolism
  • Spiro Compounds / pharmacology
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Infective Agents
  • Aza Compounds
  • Spiro Compounds