Detection of kinase activity using versatile fluorescence quencher probes

Angew Chem Int Ed Engl. 2010 Jul 5;49(29):4919-23. doi: 10.1002/anie.201000879.

Authors

Hyun-Woo Rhee¹, Seung Hwan Lee, Ik-Soo Shin, So Jung Choi, Hun Hee Park, Kyungja Han, Tai Hyun Park, Jong-In Hong

Affiliation

¹ Department of Chemistry, School of Chemical & Biological Engineering, Seoul National University, Seoul 151-747, Korea.

PMID: 20540130
DOI: 10.1002/anie.201000879

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Calcium-Calmodulin-Dependent Protein Kinase Type 2 / metabolism
Casein Kinase II / metabolism
Cyclic AMP-Dependent Protein Kinases / metabolism
Fluorescent Dyes / chemistry*
Heterocyclic Compounds, 3-Ring / chemistry
Humans
Microfluidic Analytical Techniques / methods*
Neoplasms / diagnosis
Neoplasms / enzymology
Phosphorylation
Protein Kinase Inhibitors / chemistry
Protein Kinase Inhibitors / pharmacology
Protein Kinases / chemistry
Protein Kinases / metabolism*
Proto-Oncogene Proteins c-abl / metabolism
Rhodamines

Substances

Fluorescent Dyes
Heterocyclic Compounds, 3-Ring
Protein Kinase Inhibitors
Rhodamines
tetramethylrosamine
Protein Kinases
Proto-Oncogene Proteins c-abl
Casein Kinase II
Cyclic AMP-Dependent Protein Kinases
Calcium-Calmodulin-Dependent Protein Kinase Type 2