The engineering of an orally active conotoxin for the treatment of neuropathic pain

Angew Chem Int Ed Engl. 2010 Sep 3;49(37):6545-8. doi: 10.1002/anie.201000620.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Calcium Channel Blockers / chemical synthesis
  • Calcium Channel Blockers / chemistry
  • Calcium Channel Blockers / therapeutic use
  • Conotoxins* / chemical synthesis
  • Conotoxins* / chemistry
  • Conotoxins* / therapeutic use
  • Humans
  • Molecular Structure
  • Neuralgia / drug therapy*
  • Neurons / cytology
  • Neurons / metabolism
  • Peptides* / chemical synthesis
  • Peptides* / chemistry
  • Peptides* / therapeutic use
  • Protein Conformation
  • Rats

Substances

  • Calcium Channel Blockers
  • Conotoxins
  • Peptides