Spontaneous angiographic conversion of intracranial dural arteriovenous shunt: long-term follow-up in nontreated patients

Stroke. 2010 Jul;41(7):1489-94. doi: 10.1161/STROKEAHA.110.581462. Epub 2010 Jun 3.

Abstract

Background and purpose: Dural arteriovenous shunt (DAVS) is a disease in which abnormal arteriovenous communications develop within the dura. Some case series have suggested DAVS may evolve over time, but the natural history is poorly understood. In this study, we aimed to define the incidence and clinical characteristics of patients with DAVS showing spontaneous angiographic pattern conversion.

Methods: We assessed clinical and angiographic features of patients with angiographic conversion without any treatment from a single center database consisting of 335 DAVS cases. Spontaneous angiographic conversion was defined as complete occlusion of a pre-existing DAVS or conversion of a benign into an aggressive lesion on follow-up diagnostic subtraction angiography.

Results: One hundred twelve patients were followed without treatment after the initial diagnosis of DAVS. Overall, we saw pattern conversion on angiography in 18 of the 112 cases (16.1%). Fourteen patients showed spontaneous occlusion of the shunt (12.5%); the most common locations of spontaneous obliteration were the transverse and cavernous sinuses. Four patients showed conversion to an aggressive lesion from benign DAVS (4.0%); all of these cases were associated with occlusion of the ipsilateral draining vein.

Conclusions: DAVS is a dynamic disorder, which will show chronological progression. Spontaneous angiographic obliteration or conversion into an aggressive type may occur on follow-up of untreated DAVSs.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Central Nervous System Vascular Malformations / diagnostic imaging*
  • Central Nervous System Vascular Malformations / etiology
  • Cerebral Angiography* / methods
  • Child
  • Child, Preschool
  • Dura Mater / blood supply
  • Dura Mater / diagnostic imaging*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Time Factors
  • Treatment Outcome
  • Young Adult