[Body composition in females with 21-hydroxylase deficiency: comparison of anthropometric methods and bioelectric impedance in relation to a control group]

Arq Bras Endocrinol Metabol. 2010 Mar;54(3):274-81. doi: 10.1590/s0004-27302010000300005.
[Article in Portuguese]

Abstract

Objective: To estimate body composition by evaluating skinfold thickness (ST) and electric bioimpedance (EB) in a group of women with congenital adrenal hyperplasia due to classical 21-hydroxylase deficiency (CAH-C-21OHD) in relation to a control group.

Subjects and methods: Sixteen patients and 26 controls were evaluated, all female, with age varying from 8 to 18 years. Fat (FM) and lean (LM) masses were evaluated by ST and EB. FM and LM data were analyzed in relative (%) and absolute (kg) values, and in relation to stature (FMI and LMI).

Results: There were no observed significant differences between the two methods in each group. In relation to the control group, CAH-C-21OHD patients showed higher values for FM (%) EB, FMI EB and LMI ST but lower values for FM (%) EB. Positive and high correlation values were observed for all parameters analyzed.

Conclusion: ST and EB results observed were similar in this sample of females with CAH-C-21OHD, but controversial in relation to the control group, suggesting caution when using these methods to evaluate body composition in this population.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adrenal Hyperplasia, Congenital / pathology*
  • Anthropometry / methods*
  • Body Composition / physiology*
  • Case-Control Studies
  • Child
  • Cross-Sectional Studies
  • Electric Impedance
  • Female
  • Humans
  • Skinfold Thickness