Abstract
Xenotropic murine leukemia virus-related gammaretrovirus (XMRV) has been recently associated with prostate cancer and chronic fatigue syndrome. To identify nucleic acid sequences, we examined respiratory secretions by using PCR. XMRV-specific sequences were detected in 2%-3% of samples from 168 immunocompetent carriers and approximately 10% of samples from 161 immunocompromised patients.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Bronchoalveolar Lavage Fluid / virology
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Genes, gag
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Humans
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Leukemia Virus, Murine / genetics
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Leukemia Virus, Murine / isolation & purification*
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Middle Aged
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Phylogeny
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RNA, Viral / analysis
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RNA, Viral / genetics
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Respiratory System / virology*
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Respiratory Tract Infections / complications
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Retroviridae Infections / complications
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Retroviridae Infections / epidemiology*
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Retroviridae Infections / transmission
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Retroviridae Infections / virology
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Sequence Analysis, RNA
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Sputum / virology
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Tumor Virus Infections / complications
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Tumor Virus Infections / epidemiology*
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Tumor Virus Infections / transmission
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Tumor Virus Infections / virology