Asymmetric organocatalytic Michael addition of anthrone to enone

Org Biomol Chem. 2010 Jul 21;8(14):3244-50. doi: 10.1039/b927421a. Epub 2010 May 21.

Abstract

Catalyzed by the bifunctional tertiary amino-thiourea organocatalyst derived from epicinchona alkaloid, the asymmetric Michael addition of anthrone to enone was achieved in high yield with excellent enantioselectivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthracenes / chemistry*
  • Catalysis
  • Cinchona Alkaloids / chemistry
  • Cross-Linking Reagents / chemistry
  • Ketones / chemistry*
  • Stereoisomerism
  • Thiourea / chemistry

Substances

  • Anthracenes
  • Cinchona Alkaloids
  • Cross-Linking Reagents
  • Ketones
  • anthrone
  • Thiourea