Abstract
Neurons usually migrate and differentiate in one particular encephalic vesicle. We identified a murine population of diencephalic neurons that colonized the telencephalic amygdaloid complex, migrating along a tangential route that crosses a boundary between developing brain vesicles. The diencephalic transcription factor OTP was necessary for this migratory behavior.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amygdala / embryology*
-
Amygdala / physiology
-
Animals
-
Cell Count
-
Cell Movement / physiology*
-
Diencephalon / embryology*
-
Diencephalon / physiology
-
Electroporation
-
Homeodomain Proteins / genetics
-
Homeodomain Proteins / metabolism*
-
Hypothalamus / embryology
-
Hypothalamus / physiology
-
Immunohistochemistry
-
In Situ Hybridization
-
In Vitro Techniques
-
Mice
-
Mice, Inbred C57BL
-
Mice, Knockout
-
Mice, Transgenic
-
Nerve Tissue Proteins / genetics
-
Nerve Tissue Proteins / metabolism*
-
Neurons / physiology*
-
RNA Interference
-
Stem Cell Niche / embryology
-
Stem Cell Niche / physiology
-
Telencephalon / embryology*
-
Telencephalon / physiology
Substances
-
Homeodomain Proteins
-
Nerve Tissue Proteins
-
Otp protein, mouse