Cutaneous malasseziasis: four case reports of atypical dermatitis and onychomycosis caused by Malassezia

Int J Dermatol. 2010 Feb;49(2):141-5. doi: 10.1111/j.1365-4632.2009.04178.x.

Abstract

Background: This study investigates four special cases associated with Malassezia.

Methods: The special clinical manifestations, mycologic examination, and treatment were reviewed intensively.

Results: An abundance of Malassezia hyphae were found in the scales of the three cases presenting with erythematous patches and in another case presenting with dystrophic nails. Malassezia globosa was identified and confirmed by culture. Antifungal agents were effective in the treatment of all cases.

Conclusions: Malassezia is an opportunistic fungus that may induce dermatosis other than classical pityriasis versicolor. Hyphae from the lesions may be induced by a change in the microenvironment of the fungus caused by the local application of corticosteroids.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Adult
  • Biopsy, Needle
  • Child, Preschool
  • Dermatomycoses / diagnosis*
  • Dermatomycoses / drug therapy
  • Female
  • Follow-Up Studies
  • Hand Dermatoses / diagnosis*
  • Hand Dermatoses / drug therapy
  • Humans
  • Immunohistochemistry
  • Ketoconazole / therapeutic use
  • Malassezia / isolation & purification*
  • Male
  • Mycological Typing Techniques
  • Onychomycosis / diagnosis*
  • Onychomycosis / drug therapy
  • Sampling Studies
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Ketoconazole