Time to stable ST-segment recovery following primary angioplasty is predictive of regional wall motion score and clinical outcome

Angiology. 2010 Oct;61(7):638-42. doi: 10.1177/0003319710369099. Epub 2010 May 12.

Abstract

We report the time to stable ST-segment reperfusion (TSTR) after primary angioplasty and its relationship with the clinical results; 137 patients who underwent primary angioplasty were included as part of the analysis. All patients had 24 hours ST-segment monitoring. Time to stable STR was defined as the beginning of ST-segment reperfusion (STR) lasting >4 hours without ST-segment reelevation. Six-month mortality was associated with slower TSTR (median 166.5 vs 6 minute, P = .001). Time to stable STR cutoff value of 136.5 minutes was identified as the best mortality predictor (area under the curve: 0.86, P = .001). Multivariate analysis identified Killip class > or = 2 (P = .042), TSTR cutoff value (P = .002), and final thrombolysis myocardial infarction (TIMI) flow grade III (P = .067) as predictors of 6-month mortality. Time to stable STR may be a novel continuous electrocardiogram (ECG) parameter following primary angioplasty, which can identify high-risk patients that need to be considered for additional treatments.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Angioplasty, Balloon, Coronary
  • Coronary Angiography
  • Electrocardiography*
  • Hemofiltration / instrumentation
  • Humans
  • Male
  • Middle Aged
  • Myocardial Contraction
  • Myocardial Infarction / mortality
  • Myocardial Infarction / therapy*
  • Myocardial Reperfusion*
  • Recovery of Function
  • Risk Assessment
  • Time Factors
  • Treatment Outcome