Induction of CXCL10 secretion by interferon-γ and tumour necrosis factor-α and its inhibition by peroxisome proliferator-activated receptor-γ agonists in cultured scleroderma fibroblasts

Br J Dermatol. 2010 Sep;163(3):650-1. doi: 10.1111/j.1365-2133.2010.09844.x. Epub 2010 May 8.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Chemokine CXCL10 / antagonists & inhibitors
  • Chemokine CXCL10 / metabolism*
  • Female
  • Fibrinolytic Agents / pharmacology*
  • Fibroblasts / drug effects*
  • Fibroblasts / immunology
  • Humans
  • Interferon-gamma / pharmacology*
  • Male
  • Middle Aged
  • PPAR gamma / agonists*
  • Rosiglitazone
  • Scleroderma, Systemic / immunology*
  • Thiazolidinediones / pharmacology
  • Tumor Necrosis Factor-alpha / pharmacology*

Substances

  • Chemokine CXCL10
  • Fibrinolytic Agents
  • PPAR gamma
  • Thiazolidinediones
  • Tumor Necrosis Factor-alpha
  • Rosiglitazone
  • Interferon-gamma