Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1

Biomol NMR Assign. 2010 Apr;4(1):29-32. doi: 10.1007/s12104-009-9194-0. Epub 2009 Nov 22.

Abstract

The voltage dependent anion channel (VDAC) forms a channel for metabolites and nutrients in the outer membrane of mitochondria, and it is also involved in apoptotic pathways. Here, we report sequence-specific NMR assignments for the isoform 1 of human VDAC reconstituted in lauryldimethylamine oxide (LDAO) detergent micelles. The assignments were deposited in the BMRB data base with accession number 16381.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Protein
  • Dimethylamines
  • Humans
  • Micelles
  • Nuclear Magnetic Resonance, Biomolecular
  • Protein Folding
  • Protein Isoforms / chemistry
  • Protein Structure, Secondary
  • Voltage-Dependent Anion Channel 1 / chemistry*

Substances

  • Dimethylamines
  • Micelles
  • Protein Isoforms
  • VDAC1 protein, human
  • dodecyldimethylamine oxide
  • Voltage-Dependent Anion Channel 1