Estimating continuous 4D wall motion of cerebral aneurysms from 3D rotational angiography

Med Image Comput Comput Assist Interv. 2009;12(Pt 1):140-7. doi: 10.1007/978-3-642-04268-3_18.

Abstract

This paper presents a technique to recover dynamic 3D vascular morphology from a single 3D rotational X-ray angiography acquisition. The dynamic morphology corresponding to a canonical cardiac cycle is represented via a 4D B-spline based spatiotemporal deformation. Such deformation is estimated by simultaneously matching the forward projections of a sequence of the temporally deformed 3D reference volume to the entire 2D measured projection sequence. A joint use of two acceleration strategies is also proposed: semi-precomputation of forward projections and registration metric computation based on a narrow-band region-of-interest. Digital and physical phantoms of pulsating cerebral aneurysms have been used for evaluation. Accurate estimation has been obtained in recovering sub-voxel pulsation, even from images with substantial intensity inhomogeneity. Results also demonstrate that the acceleration strategies can reduce memory consumption and computational time without degrading the performance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Artificial Intelligence
  • Cardiac-Gated Imaging Techniques / methods*
  • Cerebral Angiography / methods*
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Intracranial Aneurysm / diagnostic imaging*
  • Movement
  • Pattern Recognition, Automated / methods*
  • Radiographic Image Enhancement / methods
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Reproducibility of Results
  • Rotation
  • Sensitivity and Specificity
  • Subtraction Technique
  • Tomography, X-Ray Computed / methods*