Abstract
Enantioenriched homoallylic ethers containing a alpha,beta-unsaturated ester (syn-vinylogous aldol products) were directly accessed by Lewis acid catalyzed crotylation utilizing chiral silane 2. The reagents were prepared by enantioselective Si-H insertion to an alpha-diazovinylacetates using Davies' Rh(2)(DOSP)(4) catalyst or chiral Cu(I) Schiff base complex.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Aldehydes / chemistry*
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Copper / chemistry*
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Hydrogen / chemistry*
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Methane / analogs & derivatives*
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Methane / chemistry
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Rhenium / chemistry*
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Silanes / chemistry*
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Silicones / chemistry*
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Stereoisomerism
Substances
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Aldehydes
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Silanes
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Silicones
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crotylsilane
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carbene
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Rhenium
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Copper
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Hydrogen
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3-hydroxybutanal
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Methane