Bulk modulus and volume variation measurement of the liver and the kidneys in vivo using abdominal kinetics during free breathing

Comput Methods Programs Biomed. 2010 Nov;100(2):149-57. doi: 10.1016/j.cmpb.2010.03.003. Epub 2010 Apr 3.

Abstract

This article presents a method of predictive simulation, patient-dependant, in real time of the abdominal organ positions during free breathing. The method, that considers both influence of the abdominal breathing and thoracic breathing, needs a tracking of the patient skin and a model of the patient-specific modification of the diaphragm shape. From a measurement of the abdomen viscera kinematic during free breathing, we evaluate through a finite element analysis, the stress field sustained by the organs for a hyperelastic mechanical behaviour using large strain theory. From this analysis, we deduce an in vivo Poisson's ratio and a homogeneous bulk modulus of the liver and kidneys, and compare it to the ones in vitro available in the literature.

MeSH terms

  • Abdomen / anatomy & histology
  • Abdomen / physiology*
  • Biomechanical Phenomena
  • Humans
  • Kidney / anatomy & histology*
  • Kidney / diagnostic imaging
  • Liver / anatomy & histology*
  • Liver / diagnostic imaging
  • Respiration*
  • Tomography, X-Ray Computed