[Radiofrequency ablation as a palliative therapy option in ENT tumors: in vivo and in vitro testing]

HNO. 2010 Apr;58(4):358-63. doi: 10.1007/s00106-009-2067-0.
[Article in German]

Abstract

Background: High frequency thermotherapy (HFTT) is an established palliative therapy for hepatic malignancies. An in vivo and in vitro trial examined the preconditions for the application of HFTT with liquid-cooled wet electrodes for minimally invasive palliation of head and neck tumors.

Material and method: HFTT was applied with needle electrodes, cooled with isotonic saline solution, and a high-frequency generator (Elektrotom HiTT 106, Berchtold, Tuttlingen) to porcine tongue and narcotized, juvenile domestic pigs to the tongue and neck, and monitored in realtime by B-mode ultrasound.

Results: The direction of spread of the hyperthermic zone is well observed using ultrasound. Determining the direction of spread is not possible with cooled-tip electrode needles. Severe complications were not observed during the application.

Conclusion: RFA with liquid-cooled needle applicators is not safely applicable for the therapy of head and neck tumors.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Catheter Ablation / adverse effects
  • Catheter Ablation / methods*
  • Female
  • Head and Neck Neoplasms / diagnosis
  • Head and Neck Neoplasms / surgery*
  • Humans
  • Palliative Care / methods*
  • Treatment Outcome
  • Young Adult