Valve-sparing operation for aortic root aneurysm in patients with Marfan syndrome

Thorac Cardiovasc Surg. 2010 Mar;58(2):76-80. doi: 10.1055/s-0029-1186277. Epub 2010 Mar 23.

Abstract

Background: We report our experience with aortic valve-sparing procedures in patients with Marfan syndrome and aortic root aneurysm.

Methods: Between August 2003 and July 2007, we performed aortic valve-sparing procedures in 20 patients with aortic root aneurysm resulting from Marfan syndrome. Mean age was 28 +/- 10 years (range, 10 to 57 years), and there were 9 females and 11 males. A reimplantation technique was used in 9 cases, a remodeling technique in 8 and a patch technique in 3 cases. Additional procedures included total aorta replacement in 1 patient, and aortic arch replacement plus stented elephant trunk in 2 patients. The mean follow-up time was 46 +/- 16 months (range, 17 to 64 months).

Results: No in-hospital or late death occurred. Reexploration for bleeding was required in one case on postoperative day 1. No valve-related complications occurred during the follow-up period. At the end of follow-up, trivial or no aortic regurgitation was demonstrated in 14 patients, mild in 4 patients, moderate in 1 and severe in 1. Two patients with moderate and severe aortic regurgitation required reoperation.

Conclusions: The early and mid-term results of the valve-sparing operations were favorable, and the durability of the preserved valve should encourage use of this technique in patients with Marfan syndrome.

MeSH terms

  • Adolescent
  • Adult
  • Aortic Aneurysm / diagnosis
  • Aortic Aneurysm / etiology
  • Aortic Aneurysm / surgery*
  • Aortic Valve / surgery*
  • Aortic Valve Insufficiency / diagnosis
  • Aortic Valve Insufficiency / etiology
  • Aortic Valve Insufficiency / surgery*
  • Blood Vessel Prosthesis Implantation
  • Child
  • Female
  • Humans
  • Male
  • Marfan Syndrome / complications*
  • Middle Aged
  • Reoperation
  • Replantation
  • Retrospective Studies
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome
  • Vascular Surgical Procedures* / adverse effects
  • Young Adult