Screening for renal insufficiency following ESUR (European Society of Urogenital Radiology) guidelines with on-site creatinine measurements in an outpatient setting

Eur Radiol. 2010 Aug;20(8):1926-33. doi: 10.1007/s00330-010-1754-2. Epub 2010 Mar 23.

Abstract

Objective: To report the results and implications for workflow following introduction of ESUR guidelines to screen for potential renal insufficiency (RI) in private practice with on-site creatinine measurements.

Methods: A total of 1,766 consecutive outpatients scheduled for contrast-enhanced CT (CECT) completed the ESUR questionnaire enquiring about kidney disease, renal surgery, proteinuria, diabetes mellitus, hypertension, gout or use of nephrotoxic drugs. Patients with positive risk factors underwent on-site creatinine measurement and calculation of estimated glomerular filtration rate (eGFR). Attending radiologists adapted subsequent imaging depending on renal function and presence of risk factors.

Results: One or more ESUR risk factors were present in 796 (45.1%) patients, including hypertension (37.7%), nephrotoxic medication (21.3%), diabetes mellitus (8.0%), proteinuria (3.9%), renal disease (4.1%), gout (3.1%) and renal surgery (2.6%). Pre-procedural creatinine measurements revealed severe RI (eGFR < 30 ml min(-1) 1.73 m(-2)) in 10 (1.3%) and moderate RI (eGFR 30-59 ml min(-1) 1.73 m(-2)) in 106 (13.8%). Imaging work-up was adapted in 132 (16.6%) as follows: reduction of contrast material dose (n = 85), CT without contrast (n = 40), changeover to MRI (n = 3) or scintigraphy (n = 4).

Conclusion: Screening for RI following ESUR guidelines requires creatinine measurements in nearly half of outpatients scheduled for CECT and reveals moderate to severe renal impairment in 6.6%.

MeSH terms

  • Ambulatory Care / standards
  • Ambulatory Care / statistics & numerical data
  • Biomarkers / blood
  • Creatinine / blood*
  • Europe
  • Female
  • Humans
  • Male
  • Mass Screening / methods
  • Mass Screening / standards*
  • Mass Screening / statistics & numerical data*
  • Middle Aged
  • Outpatients / statistics & numerical data
  • Practice Guidelines as Topic*
  • Prevalence
  • Renal Insufficiency / blood*
  • Renal Insufficiency / diagnosis*
  • Renal Insufficiency / epidemiology
  • Risk Assessment / methods
  • Risk Assessment / standards
  • Risk Factors
  • Surveys and Questionnaires / standards*
  • Switzerland / epidemiology
  • Tomography, X-Ray Computed / statistics & numerical data

Substances

  • Biomarkers
  • Creatinine