Boronic acid catalyzed ene carbocyclization of acetylenic dicarbonyl compounds

Chem Commun (Camb). 2010 Apr 7;46(13):2191-3. doi: 10.1039/b924899d. Epub 2010 Feb 25.

Abstract

The discovery and development of an efficient ene carbocyclization of 1,3-dicarbonyl compounds bearing pendent terminal alkyne substituents under 3-nitrobenzeneboronic acid catalysis is described. The reaction is efficient, easy to perform and general to a wide range of ketoester substrates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry*
  • Boronic Acids / chemistry*
  • Catalysis
  • Cyclization
  • Ketones / chemistry

Substances

  • Alkynes
  • Boronic Acids
  • Ketones
  • 3-nitrobenzeneboronic acid