Mycosis fungoides: cutaneous T-cell lymphoma

Am Fam Physician. 1991 May;43(5):1703-7.

Abstract

Most patients with mycosis fungoides are between 40 and 60 years of age. The disease has three clinical stages: (1) the premycotic, or patch, stage, consisting of macular, scaling, faint pink to red pruritic patches, usually on unexposed surfaces; (2) the mycotic, or plaque, stage, consisting of reddish, purple-brown plaques, often annular in shape and symmetric in distribution, and (3) the tumor stage, consisting of red-brown to violaceous, dome-shaped, firm tumors with a predilection for the face and body folds. The Sézary syndrome is a leukemic variant. Treatment depends on the extent of disease and includes topical or systemic chemotherapy, radiotherapy and psoralen plus long-wave ultraviolet light therapy.

MeSH terms

  • Adult
  • Biopsy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mycosis Fungoides / classification
  • Mycosis Fungoides / diagnosis
  • Mycosis Fungoides / pathology*
  • Neoplasm Metastasis
  • Neoplasm Staging
  • Prognosis
  • Sezary Syndrome / pathology
  • Skin Neoplasms / classification
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / pathology*