Aqueous solubilization of photochromic compounds by bile salt aggregates

Chem Commun (Camb). 2010 Mar 21;46(11):1941-3. doi: 10.1039/b926351a. Epub 2010 Feb 8.

Abstract

Bile salts form aggregates in aqueous solutions which were shown to efficiently solubilize aqueous insoluble photochromic compounds. Photochromic switching was observed for a spiropyran and a diarylethene. In the case of the spiropyran, the incorporation into the bile salt aggregate led to improved hydrolytic stability and changes in thermal rate constants.