Sphincter of Oddi laxity: an important factor in hepatolithiasis

World J Gastroenterol. 2010 Feb 28;16(8):1014-8. doi: 10.3748/wjg.v16.i8.1014.

Abstract

Aim: To evaluate the importance of sphincter of Oddi laxity (SOL) in hepatolithiasis (HL).

Methods: Subjects included 98 patients diagnosed with HL between 2002 and 2007. Detailed histories were taken and the subjects were monitored until July 2008. HL patients were divided into two groups: Group I included 45 patients with SOL, and Group II included 53 patients without. Recurrence and reoperation indices of both groups were calculated and compared.

Results: The recurrence index was 0.135 in Group I and 0.018 in Group II (P < 0.001). The reoperation index was 0.070 in Group I and 0.010 in Group II (P < 0.001). The mean frequency of biliary operation was 2.07 in Group I and 1.21 in Group II (P = 0.001). Differences between the two groups are significant.

Conclusion: HL patients with SOL tend to have a higher risk of recurrence and a larger demand for reoperation than those without this condition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Lithiasis* / physiopathology
  • Lithiasis* / prevention & control
  • Lithiasis* / surgery
  • Liver Diseases* / physiopathology
  • Liver Diseases* / prevention & control
  • Liver Diseases* / surgery
  • Male
  • Middle Aged
  • Recurrence
  • Sphincter of Oddi / pathology
  • Young Adult