Functional parameters of the left ventricle: comparison of cardiac MRI and cardiac CT in a large population

Radiol Med. 2010 Aug;115(5):702-13. doi: 10.1007/s11547-010-0525-0. Epub 2010 Feb 22.
[Article in English, Italian]

Abstract

Purpose: The authors sought to compare magnetic resonance imaging (MRI) and computed tomography (CT) for assessing left ventricular (LV) function parameters in a large patient population.

Materials and methods: The study was conducted on 181 patients who underwent cardiac MRI and cardiac CT for various indications. For MRI, we used two-dimensional cine balanced steady-state free precession (b-SSFP) sequences, and for CT we used multiphase short-axis reconstructions. Volume data sets were evaluated with dedicated software. Results were compared with a paired, two-tailed Student's t test, Pearson's correlation (r), and Bland-Altman analysis.

Results: A high level of concordance was observed between cardiac MRI and CT. Ejection fraction (EF) was 53+/-14% for MRI vs. 53%+/-15% for CT. There was good correlation for EF (r=0.71; p>0.05) and end-systolic volume (r=0.74; p>0.05). End-diastolic volume (74+/-23 ml at MRI vs. 71+/-19 ml at CT; r=0.58; p<0.05) and myocardial mass (63+/-20 g at MRI and 56+/-18 g at CT; r=0.89; p<0.01) showed statistically significant differences, although the discrepancy had no clinical impact.

Conclusions: MRI and CT show a good level of agreement in assessing LV function parameters, and both can be used interchangeably in clinical practice.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Contrast Media
  • Coronary Angiography
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted
  • Iopamidol / analogs & derivatives
  • Magnetic Resonance Imaging, Cine / methods*
  • Male
  • Middle Aged
  • Prospective Studies
  • Tomography, X-Ray Computed / methods*
  • Ventricular Dysfunction, Left / diagnosis*
  • Ventricular Dysfunction, Left / diagnostic imaging

Substances

  • Contrast Media
  • iomeprol
  • Iopamidol