HLA-DRB1*11: a strong risk factor for acquired severe ADAMTS13 deficiency-related idiopathic thrombotic thrombocytopenic purpura in Caucasians

J Thromb Haemost. 2010 Apr;8(4):856-9. doi: 10.1111/j.1538-7836.2010.03772.x. Epub 2010 Feb 6.

Authors

P Coppo, M Busson, A Veyradier, A Wynckel, P Poullin, E Azoulay, L Galicier, P Loiseau; French Reference Centre For Thrombotic Microangiopathies

Collaborators

French Reference Centre For Thrombotic Microangiopathies:
E Azoulay, D Bordessoule, F Brivet, M Buffet, A Bussel, P Coppo, C Charasse, G Choukroun, K Clabault, C Daubin, A Devidas, O Fain, V Frémeaux-Bacchi, B Guidet, D Gruson, M Hamidou, F Heshmati, N Ifrah, J-M Korach, V Le Guern, S Malot, P-J Mira, M Monge, B Moulin, C Mousson, H Nivet, M Ojeda-Uribe, A Ouchenir, J-B Palcoux, P Poullin, J Pourrat, C Pouteil-Noble, F Provôt, M Ramakers, B Regnier, J-A Ribeil, E Rondeau, B Schlemmer, T Leblanc, J-P Vernant, A Veyradier, C Vigneau, F Vincent, A Wynckel, M Wolf, P Zunic

PMID: 20141578
DOI: 10.1111/j.1538-7836.2010.03772.x

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

ADAM Proteins / deficiency*
ADAMTS13 Protein
Case-Control Studies
Chi-Square Distribution
Enzyme-Linked Immunosorbent Assay
France / epidemiology
Gene Frequency
Genetic Predisposition to Disease
HLA-DR Antigens / genetics*
HLA-DRB1 Chains
Humans
Odds Ratio
Phenotype
Purpura, Thrombocytopenic, Idiopathic / enzymology
Purpura, Thrombocytopenic, Idiopathic / ethnology
Purpura, Thrombocytopenic, Idiopathic / genetics*
Purpura, Thrombocytopenic, Idiopathic / immunology
Registries
Risk Assessment
Risk Factors
White People / genetics*

Substances

HLA-DR Antigens
HLA-DRB1 Chains
HLA-DRB1*11 antigen
ADAM Proteins
ADAMTS13 Protein
ADAMTS13 protein, human