[Dermal fibroblasts exert a key influence in the development of basal-cell skin cancers: the model of Gorlin syndrome]

Med Sci (Paris). 2010 Jan;26(1):22-5. doi: 10.1051/medsci/201026122.
[Article in French]
No abstract available

Publication types

  • News

MeSH terms

  • Basal Cell Nevus Syndrome / genetics
  • Basal Cell Nevus Syndrome / pathology*
  • Cell Differentiation
  • Chemokine CXCL12 / physiology
  • Dermis / pathology*
  • Fibroblast Growth Factor 7 / physiology
  • Fibroblasts / enzymology
  • Fibroblasts / physiology*
  • Genomic Instability
  • Hedgehog Proteins / physiology
  • Humans
  • Intercellular Signaling Peptides and Proteins / physiology
  • Matrix Metalloproteinase 1 / metabolism
  • Matrix Metalloproteinase 3 / metabolism
  • Neoplasm Proteins / metabolism
  • Patched Receptors
  • Receptors, Cell Surface / deficiency
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / physiology
  • Receptors, G-Protein-Coupled / physiology
  • Skin Neoplasms / genetics
  • Skin Neoplasms / pathology*
  • Smoothened Receptor
  • Tenascin / physiology
  • Transcription, Genetic
  • Tumor Suppressor Proteins / deficiency
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / physiology

Substances

  • Chemokine CXCL12
  • FGF7 protein, human
  • GREM1 protein, human
  • Hedgehog Proteins
  • Intercellular Signaling Peptides and Proteins
  • Neoplasm Proteins
  • Patched Receptors
  • Receptors, Cell Surface
  • Receptors, G-Protein-Coupled
  • SHH protein, human
  • SMO protein, human
  • Smoothened Receptor
  • Tenascin
  • Tumor Suppressor Proteins
  • Fibroblast Growth Factor 7
  • MMP3 protein, human
  • Matrix Metalloproteinase 3
  • MMP1 protein, human
  • Matrix Metalloproteinase 1