Background: Early virologic response to pegylated interferon in the treatment of chronic hepatitis B infection is not frequently reported.
Method: The case notes of the patients was retrieved and relevant data extracted, literature review was done using Medline.
Result: A report of a case of early virologic response in a 62 year old man with chronic hepatitis B infection, receiving pegylated interferon is presented with a review of the relevant literature. He had HBV DNA level assessed by PCR and histology of liver biopsy specimen.
Conclusion: Clinicians should be on the lookout for early virologic response to pegylated interferon and the eventual outcome of such early response.