Synthesis of some new mono- and bis-polycyclic aromatic spiro and bis-nonspiro-beta-lactams

Molecules. 2010 Jan 22;15(1):515-31. doi: 10.3390/molecules15010515.

Abstract

Some new mono-and bis-polycyclic aromatic spiro-beta-lactams and bis-non spiro-polycyclic aromatic beta-lactams have been synthesized from imines derived from anthracene-9-carbaldehyde, 2-naphtaldehyde and a ketene derived from 9H-xanthene-9-carboxylic acid and phenoxyacetic acid by a [2+2] cycloaddition reaction. The cycloadducts were characterized by spectral data, including 1H-NMR, 13C-NMR, IR and elemental analyses. The configurations of some of these mono-spiro-beta-lactams were established by X-ray crystal analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Models, Molecular
  • Spiro Compounds / chemical synthesis*
  • Spiro Compounds / chemistry
  • beta-Lactams / chemical synthesis*
  • beta-Lactams / chemistry

Substances

  • Spiro Compounds
  • beta-Lactams