Findings of clinical trials that evaluate the impact of medical therapies on progression of atherosclerosis

Curr Med Res Opin. 2010 Mar;26(3):745-51. doi: 10.1185/03007990903547616.

Abstract

Background: Arterial wall imaging has been increasingly employed in clinical trials to evaluate the impact of medical therapies on progression of atherosclerosis.

Scope: A selective overview of major findings from clinical trials that assessed the impact of medical therapies on atherosclerosis progression.

Findings: Targeting established risk factors including LDL cholesterol, HDL cholesterol and blood pressure has a beneficial impact on disease progression.

Conclusion: As a result, vascular imaging has been employed in the early evaluation of experimental therapies.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Angiography / methods
  • Atherosclerosis / blood
  • Atherosclerosis / diagnostic imaging*
  • Atherosclerosis / physiopathology
  • Atherosclerosis / therapy*
  • Blood Pressure
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Female
  • Humans
  • Male
  • Risk Factors

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL