Abstract
Non-steroidal anti-inflammatory drugs frequently cause adverse reactions. This retrospective study was based on analysis of the data obtained from interviews conducted with 173 patients, who underwent and tolerated a challenge test with etoricoxib (a selective cyclooxigenase 2 enzyme inhibitor). Only one of 82 patients who were treated with etoricoxib reported reactions. We can conclude that etoricoxib shows a high long-term tolerability in patients with non-steroidal anti-inflammatory drug hypersensitivity.
MeSH terms
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Administration, Oral
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
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Cyclooxygenase 2 Inhibitors / administration & dosage
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Cyclooxygenase 2 Inhibitors / adverse effects
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Cyclooxygenase 2 Inhibitors / therapeutic use*
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Drug Hypersensitivity / etiology*
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Etoricoxib
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Female
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Humans
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Male
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Middle Aged
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Pyridines / administration & dosage
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Pyridines / adverse effects
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Pyridines / therapeutic use*
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Retrospective Studies
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Single-Blind Method
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Sulfones / administration & dosage
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Sulfones / adverse effects
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Sulfones / therapeutic use*
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Young Adult
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Cyclooxygenase 2 Inhibitors
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Pyridines
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Sulfones
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Etoricoxib