Case of small bowel perforation due to enteropathy-type T-cell lymphoma

Yonsei Med J. 2009 Dec 31;50(6):859-61. doi: 10.3349/ymj.2009.50.6.859. Epub 2009 Dec 18.

Abstract

Enteropathy-type T-cell lymphoma (ETTL) is a rare disease with a poor prognosis. According to the World Health Organization (WHO) classification, it is a subtype of the peripheral T-cell lymphomas. This disease is associated with gluten-sensitive enteropathy, has a high risk of intestinal perforation and obstruction, and is refractory to chemotherapeutic treatment. We report the case of a 73-year-old woman who was diagnosed with enteropathy-type T-cell lymphoma of the small intestine, which was positive for the markers of cytotoxic T cells, CD3, CD8, and CD56, on immunohistochemical staining after resection of the perforated terminal ileum.

Keywords: Enteropathy-type T-cell lymphoma; celiac disease; intestinal perforation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Celiac Disease / complications*
  • Celiac Disease / pathology
  • Female
  • Gastrointestinal Neoplasms / complications*
  • Gastrointestinal Neoplasms / pathology
  • Humans
  • Intestinal Perforation / diagnosis*
  • Intestinal Perforation / etiology*
  • Intestinal Perforation / pathology
  • Lymphoma, T-Cell / complications*
  • Lymphoma, T-Cell / pathology