Therapeutic options of caesarean scar pregnancy: case series and literature review

J Clin Ultrasound. 2010 Feb;38(2):75-84. doi: 10.1002/jcu.20648.

Abstract

We describe our experience with the treatment of 4 caesarean scar pregnancies and provide an overview of current literature. Four women diagnosed with a caesarean scar pregnancy in our hospital between 1996 and 2007 were treated with local or systemic methotrexate and had a steady decline of the serum beta-hCG level. The uterus was preserved in all women and 3 of them had an uneventful subsequent pregnancy and delivery. We suggest that transcervical needle aspiration of amniotic fluid followed by intra-amniotic injection of methotrexate should be the treatment of choice, followed by surgical treatment only if methotrexate fails.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adult
  • Amnion
  • Antimetabolites, Antineoplastic / administration & dosage
  • Antimetabolites, Antineoplastic / therapeutic use
  • Cesarean Section / adverse effects*
  • Cicatrix / complications*
  • Cicatrix / diagnostic imaging
  • Endosonography
  • Female
  • Follow-Up Studies
  • Humans
  • Injections
  • Laparotomy / methods*
  • Methotrexate / administration & dosage
  • Methotrexate / therapeutic use*
  • Myometrium
  • Pregnancy
  • Pregnancy, Ectopic / diagnostic imaging
  • Pregnancy, Ectopic / etiology
  • Pregnancy, Ectopic / therapy*

Substances

  • Antimetabolites, Antineoplastic
  • Methotrexate