Synthesis and moisture absorption and retention activities of a carboxymethyl and a quaternary ammonium derivative of alpha,alpha-trehalose

Carbohydr Res. 2010 Jan 11;345(1):120-3. doi: 10.1016/j.carres.2009.09.024. Epub 2009 Sep 25.

Abstract

Carboxymethyl alpha,alpha-trehalose (CMT) and a quaternary ammonium derivative of alpha,alpha-trehalose (QT) were successfully prepared, and their moisture absorption and retention activities were assessed. Results showed that both CMT and QT had better moisture absorption abilities at 43% and 81% relative humidity (RH) than alpha,alpha-trehalose. In addition, the two alpha,alpha-trehalose derivatives had better moisture retention abilities than alpha,alpha-trehalose under three humidity conditions: 81% RH, 43% RH, and under dry conditions. Therefore, carboxymethylation and quaternarization could improve the moisture absorption and retention abilities of alpha,alpha-trehalose. CMT and QT showed better moisture absorption ability and moisture retention ability than that of hyaluronan (HA), and could potentially find a use as moisture retention ingredient, for example, in cosmetics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorption
  • Magnetic Resonance Spectroscopy
  • Quaternary Ammonium Compounds / chemistry*
  • Spectrophotometry, Infrared
  • Trehalose / analogs & derivatives
  • Trehalose / chemical synthesis*
  • Trehalose / chemistry*

Substances

  • Quaternary Ammonium Compounds
  • Trehalose