A premature infant with fetal myocardial and abdominal calcifications and factor V Leiden homozygosity

J Perinatol. 2009 Nov;29(11):771-3. doi: 10.1038/jp.2009.62.

Abstract

We present a premature male neonate with confirmed factor V Leiden deficiency diagnosed prenatally with cardiac and abdominal calcifications. Our patient's findings suggest that clinicians consider thromboembolic conditions when multiple fetal calcifications are visualized.

Publication types

  • Case Reports

MeSH terms

  • Abruptio Placentae / diagnostic imaging
  • Abruptio Placentae / genetics
  • Adult
  • Calcinosis / diagnostic imaging
  • Calcinosis / genetics*
  • Cardiomyopathies / diagnostic imaging
  • Cardiomyopathies / genetics*
  • DNA Mutational Analysis
  • Diagnosis, Differential
  • Diaphragm* / diagnostic imaging
  • Echocardiography
  • Factor V / genetics*
  • Factor V Deficiency / diagnosis
  • Factor V Deficiency / genetics*
  • Female
  • Genotype
  • Heart Ventricles / diagnostic imaging
  • Homozygote*
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases / diagnostic imaging
  • Infant, Premature, Diseases / genetics*
  • Liver Diseases / diagnostic imaging
  • Liver Diseases / genetics*
  • Male
  • Placenta Diseases / diagnostic imaging
  • Placenta Diseases / genetics
  • Pregnancy
  • Thromboembolism / diagnostic imaging
  • Thromboembolism / genetics
  • Ultrasonography, Prenatal

Substances

  • factor V Leiden
  • Factor V