Diffusion-weighted MRI: a new tool for the diagnosis of fistula in ano

J Magn Reson Imaging. 2009 Nov;30(5):1021-6. doi: 10.1002/jmri.21934.

Abstract

Purpose: To retrospectively determine the additional value of diffusion-weighted magnetic resonance imaging (MRI) to T2-weighted imaging in the evaluation of anal fistulae in comparison with gadolinium (Gd)-enhanced imaging.

Materials and methods: Thirteen patients (mean age, 35.2 years) with 20 anal fistulae were included. The protocol consisted of fat-suppressed T2-weighted fast spin-echo, diffusion-weighted single-shot echo-planar (b factors 0 and 800 s/mm(2)), and fat-suppressed Gd-enhanced T1-weighted gradient echo sequences. Two radiologists evaluated images in consensus.

Results: Eighteen (90%) fistulae were detected on T2-weighted images, and 19 (95%) and 19 (95%) were detected on diffusion-weighted and T2-weighted images combined and on Gd-enhanced and T2-weighted images combined, respectively. There was no statistically significant difference in sensitivity of the techniques (P > 0.5 for all comparison pairs). Confidence scores with diffusion-weighted and T2-weighted images combined or those with Gd-enhanced and T2-weighted images combined were significantly greater than those with T2-weighted images alone (P = 0.0047 and 0.014, respectively).

Conclusion: Diffusion-weighted MRI of anal fistulae is a useful sequence and can be a helpful adjunct to T2-weighted imaging, especially in patients with risk factors for contrast agents.

MeSH terms

  • Adult
  • Contrast Media / pharmacology*
  • Crohn Disease / diagnosis*
  • Crohn Disease / pathology
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Humans
  • Image Enhancement / methods
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Radiology / methods*
  • Rectal Fistula / diagnosis*
  • Rectal Fistula / pathology
  • Reproducibility of Results
  • Research Design
  • Retrospective Studies

Substances

  • Contrast Media