Regioselective ruthenium-catalyzed direct benzylations of arenes through C-H bond cleavages

Lutz Ackermann; Petr Novák

doi:10.1021/ol902115f

Regioselective ruthenium-catalyzed direct benzylations of arenes through C-H bond cleavages

Org Lett. 2009 Nov 5;11(21):4966-9. doi: 10.1021/ol902115f.

Authors

Lutz Ackermann¹, Petr Novák

Affiliation

¹ Institut fuer Organische und Biomolekulare Chemie, Georg-August-Universitaet, Tammannstrasse 2, 37077 Goettingen, Germany. lutz.ackermann@chemie.uni-goettingen.de

PMID: 19810689
DOI: 10.1021/ol902115f

Abstract

Highly regioselective ruthenium-catalyzed direct benzylations through C-H bond cleavages were accomplished under remarkably mild, nonacidic reaction conditions, for which experimental studies suggested a S(E)Ar-type mechanism not to be operative.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzene Derivatives / chemical synthesis*
Benzene Derivatives / chemistry*
Catalysis
Molecular Structure
Ruthenium / chemistry*
Stereoisomerism

Substances

Benzene Derivatives
Ruthenium