Four new lignans from Viburnum foetidum var. foedidum

Chem Pharm Bull (Tokyo). 2009 Oct;57(10):1129-31. doi: 10.1248/cpb.57.1129.

Abstract

The 70% aqueous acetone extract of the aerial part of Viburnum foetidum var. foedidum afforded four new lignans (1-4) together with six known ones. The structures of the four new compounds were elucidated on the basis of 1D (dimensional), 2D-NMR, and mass spectral analysis. The structure of compound 1, with a novel spirocyclic moiety, was also confirmed by X-ray diffraction analysis. Compounds 1-10 were evaluated for their cytotoxic activity. However, none of the compounds showed significant cytotoxic activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Lignans / chemistry*
  • Lignans / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Plant Extracts / chemistry
  • Viburnum / chemistry*

Substances

  • Lignans
  • Plant Extracts