Human Plasmodium knowlesi infection detected by rapid diagnostic tests for malaria

Jaap J van Hellemond; Marijke Rutten; Rob Koelewijn; Anne Marie Zeeman; Jaco J Verweij; Pieter J Wismans; Clemens H Kocken; Perry J J van Genderen

doi:10.3201/eid1509.090358

Human Plasmodium knowlesi infection detected by rapid diagnostic tests for malaria

Emerg Infect Dis. 2009 Sep;15(9):1478-80. doi: 10.3201/eid1509.090358.

Authors

Jaap J van Hellemond¹, Marijke Rutten, Rob Koelewijn, Anne Marie Zeeman, Jaco J Verweij, Pieter J Wismans, Clemens H Kocken, Perry J J van Genderen

Affiliation

¹ Erasmus University Medical Center, Rotterdam, the Netherlands.

Abstract

We describe a PCR-confirmed case of Plasmodium knowlesi infection with a high parasitemia level and clinical signs of severe malaria in a migrant worker from Malaysian Borneo in the Netherlands. Investigations showed that commercially available rapid antigen tests for detection of human Plasmodium infections can detect P. knowlesi infections in humans.

Publication types

Case Reports

MeSH terms

Adult
Animals
Antigens, Protozoan / analysis
Borneo
Humans
Malaria / diagnosis*
Malaria / parasitology
Male
Netherlands
Parasitemia / diagnosis
Parasitemia / parasitology
Plasmodium knowlesi / genetics
Plasmodium knowlesi / isolation & purification*
Polymerase Chain Reaction / methods
Reagent Kits, Diagnostic*
Species Specificity
Time Factors
Transients and Migrants

Substances

Antigens, Protozoan
Reagent Kits, Diagnostic