Abstract
The authors describe the reactivation of obsessive-compulsive disorder (OCD) in three patients with lesions in the prefronto-subcortical circuits after decades of being asymptomatic. The patients also reported the emergence of new OCD symptoms and motor/phonic tics as well as mental rituals thematically related to the negative experience of suffering cognitive and motor deficits.
MeSH terms
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Age Factors
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Aged
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Brain / diagnostic imaging
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Brain / pathology*
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Female
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Humans
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Neural Pathways / diagnostic imaging
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Neural Pathways / pathology
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Obsessive-Compulsive Disorder / drug therapy
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Obsessive-Compulsive Disorder / pathology*
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Prefrontal Cortex / diagnostic imaging
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Prefrontal Cortex / pathology*
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Psychiatric Status Rating Scales
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Psychotropic Drugs / therapeutic use
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Recurrence
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Tomography, Emission-Computed, Single-Photon
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Tomography, X-Ray Computed
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Treatment Outcome