Visual orienting tasks reveal an impaired disengagement of attention in schizophrenia. We explored visual orientation in 20 schizophrenia patients (SZ), 20 full siblings (FS), and 20 controls (C) using a cued target detection (gap vs. no gap) and a choice reaction time task. SZ but not FS had longer reaction time with comparable reactions to warning. In contrast to C, SZ and FS did not display a significant gap effect. The disengagement deficit in schizophrenia patients and their siblings provides arguments for altered early attention mechanisms (in schizophrenic patients and their nonpsychotic relatives).