Phenytoin-induced reduction of voriconazole serum concentration is not compensated by doubling the dosage

Br J Clin Pharmacol. 2009 Sep;68(3):462-3. doi: 10.1111/j.1365-2125.2009.03464.x.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anticonvulsants / administration & dosage
  • Anticonvulsants / pharmacology*
  • Antifungal Agents / pharmacokinetics*
  • Area Under Curve
  • Dose-Response Relationship, Drug
  • Drug Interactions
  • Female
  • Humans
  • Male
  • Middle Aged
  • Phenytoin / administration & dosage
  • Phenytoin / pharmacology*
  • Pulmonary Aspergillosis / drug therapy
  • Pyrimidines / pharmacokinetics*
  • Triazoles / pharmacokinetics*
  • Voriconazole

Substances

  • Anticonvulsants
  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Phenytoin
  • Voriconazole