Catheter-associated thrombosis in patients with malignancy

J Clin Oncol. 2009 Oct 10;27(29):4858-64. doi: 10.1200/JCO.2009.22.6126. Epub 2009 Sep 8.

Abstract

Central venous catheters are widely used in the care of patients with cancer. Indwelling catheters are associated with upper extremity deep venous thrombosis in some patients, and recognition of this entity is an important aspect of treating patients with malignancies. This article will review the incidence, pathogenesis, clinical presentation, diagnosis, treatment, and prophylaxis of catheter-associated thrombosis in patients with malignancy. The care of pediatric patients with malignancy and catheter-associated thrombosis will also be addressed.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Antineoplastic Agents / administration & dosage
  • Catheterization, Central Venous / adverse effects*
  • Catheters, Indwelling / adverse effects
  • Child
  • Child, Preschool
  • Female
  • Fibrinolytic Agents / therapeutic use
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Neoplasms / diagnosis
  • Neoplasms / drug therapy*
  • Neoplasms / epidemiology
  • Phlebography / methods
  • Risk Assessment
  • Severity of Illness Index
  • Sex Distribution
  • Survival Analysis
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / epidemiology*
  • Venous Thrombosis / etiology*
  • Venous Thrombosis / prevention & control
  • Young Adult

Substances

  • Antineoplastic Agents
  • Fibrinolytic Agents