Vascular compromise as a cause of sudden death in a pediatric patient with widely metastatic testicular germ cell tumor

J Pediatr Hematol Oncol. 2009 Oct;31(10):756-7. doi: 10.1097/MPH.0b013e3181b78530.

Abstract

During hospitalization for evaluation of a large testicular tumor with extensive metastatic disease, this 14-year-old boy collapsed while showering and could not be resuscitated. At autopsy, there was no evidence of thromboembolic phenomenon, a known cause of sudden death in metastatic testicular tumors and other large abdominal tumors. However, marked compression of the inferior vena cava by a large pelvicoabdominal tumor mass and findings suggestive of systemic-portal shunting were consistent with the death due to the impaired venous return via the inferior vena cava.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Autopsy
  • Constriction, Pathologic / etiology*
  • Constriction, Pathologic / pathology
  • Death, Sudden / etiology*
  • Humans
  • Male
  • Neoplasm Metastasis
  • Neoplasms, Germ Cell and Embryonal / complications*
  • Testicular Neoplasms / complications*
  • Vascular Diseases
  • Vena Cava, Inferior / physiopathology*