No association between apolipoprotein E polymorphisms and recurrent pregnancy loss

Sebastiano Bianca; Barbara Barrano; Nunzio Cutuli; Lara Indaco; Antonella Cataliotti; Gabriella Milana; Chiara Barone; Giuseppe Ettore

doi:10.1016/j.fertnstert.2009.07.971

No association between apolipoprotein E polymorphisms and recurrent pregnancy loss

Fertil Steril. 2010 Jan;93(1):276. doi: 10.1016/j.fertnstert.2009.07.971. Epub 2009 Sep 3.

Authors

Sebastiano Bianca¹, Barbara Barrano, Nunzio Cutuli, Lara Indaco, Antonella Cataliotti, Gabriella Milana, Chiara Barone, Giuseppe Ettore

Affiliation

¹ Dipartimento Materno Infantile, Centro di Consulenza Genetica e di Teratologia della Riproduzione, Laboratorio di Citogenetica, ARNAS Garibaldi Nesima, Catania, Italy. sebastiano.bianca@tiscali.it

PMID: 19732892
DOI: 10.1016/j.fertnstert.2009.07.971

Abstract

Our study does not support the reported association between APOE and recurrent pregnancy loss (RPL) than the clinical management of these patients should not be influenced by the presence or not of APO E polymorphisms.

MeSH terms

Abortion, Habitual / genetics*
Apolipoprotein E3 / genetics*
Apolipoprotein E4 / genetics*
Case-Control Studies
Female
Genetic Predisposition to Disease
Humans
Phenotype
Polymorphism, Genetic*
Pregnancy
Risk Assessment
Risk Factors

Substances

Apolipoprotein E3
Apolipoprotein E4