Preliminary report: follow-up after dynamic cardiomyoplasty

Lancet. 1990 May 12;335(8698):1122-4. doi: 10.1016/0140-6736(90)91126-u.

Abstract

Five patients were studied 5-13 months after dynamic cardiomyoplasty for refractory heart failure. In two, muscle flap stimulation caused a pronounced increase in cardiac index (mean 55%) and ejection fraction (mean 75%); no patient showed improvement in cardiac filling pressure. 2 years after surgery, one of the patients with haemodynamic improvement died from ventricular fibrillation, and histochemistry of the stimulated muscle flap revealed predominantly fatigue-resistant type I fibres, without evidence of fibrosis. In selected cases, dynamic cardiomyopathy could be of long-term benefit.

MeSH terms

  • Adult
  • Cardiac Output
  • Cardiac Pacing, Artificial
  • Echocardiography
  • Evaluation Studies as Topic
  • Female
  • Follow-Up Studies
  • Heart Failure / mortality
  • Heart Failure / pathology
  • Heart Failure / physiopathology
  • Heart Failure / surgery*
  • Humans
  • Male
  • Middle Aged
  • Stroke Volume
  • Surgical Flaps*