Generation and reactions of trifluoromethylethenyl titanium(II) species

J Org Chem. 2009 Oct 2;74(19):7559-61. doi: 10.1021/jo901392n.

Abstract

The reaction of (trifluoromethyl)dimethylphenylsilylacetylene and (eta(2)-propene)Ti(O(i)Pr)(2) generated in situ smoothly proceeded giving the corresponding (eta(2)-1-dimethylphenylsilyl-2-trifluoromethylalkyne)Ti(O(i)Pr)(2), which reacted with aldehydes and ketones to afford the corresponding addition products in good yields with good to excellent regioselectivity.

MeSH terms

  • Molecular Structure
  • Organometallic Compounds / chemical synthesis*
  • Organometallic Compounds / chemistry*
  • Organosilicon Compounds / chemical synthesis*
  • Organosilicon Compounds / chemistry
  • Stereoisomerism
  • Titanium / chemistry*

Substances

  • Organometallic Compounds
  • Organosilicon Compounds
  • Titanium