Association of the bla(CMY-10) gene with a novel complex class 1 integron carrying an ISCR1 element in clinical isolates from Korea

Clin Microbiol Infect. 2010 Jul;16(7):1013-7. doi: 10.1111/j.1469-0691.2009.03002.x. Epub 2009 Jul 21.

Abstract

The bla(CMY-10) gene responsible for β-lactam resistance was located on a new complex class 1 integron within a conjugative plasmid. The sul1-type class 1 integron, containing an aadA2a gene cassette, was identified upstream of bla(CMY-10). A unique gene array (yqgF-yqgE-gshB-orf97--orf105) was identified downstream of bla(CMY-10.).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • DNA, Bacterial / genetics
  • Enterobacter aerogenes / drug effects
  • Enterobacter aerogenes / genetics*
  • Enterobacter aerogenes / isolation & purification
  • Enterobacteriaceae Infections / microbiology
  • Escherichia coli / genetics
  • Genes, Bacterial
  • Humans
  • Integrons / genetics*
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Republic of Korea
  • Sequence Analysis, DNA
  • beta-Lactam Resistance / genetics*
  • beta-Lactamases / genetics*

Substances

  • DNA, Bacterial
  • CMY-10 beta-lactamase
  • beta-Lactamases

Associated data

  • GENBANK/FJ004895